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Sunday sees the initial Wear-Tyne derby since 2024, but who will emerge victorious – Sunderland or Newcastle?
"For most of last season, it was unthinkable the Wearside club getting promoted and challenging with Eddie Howe's Newcastle, let alone being above them in the table," commented pundit Chris Sutton.
"It is very different now, and the way Sunderland play leads me to believe they've got a real chance."
Sutton is making predictions for all 380 Premier League games this season, in competition with artificial intelligence, fans and a range of guests.
For week 16, he faces off against England Gaming star Daniel 'Stingray' Ray.
Ray is going for glory for the national gaming squad – the Football Association's recognised esports team – at the gaming title Uefa eEuro 2025 finals tournament, which is being held at Twickenham Stadium on Saturday.
Viewers can catch Uefa's YouTube, IG Live and TikTok channels, as well as the official Twitch channel and its YouTube counterpart and England's Twitch.
Do you agree with their forecasts? Feel free to submit your own projections below.
The most commonly selected scoreline selected for each game is used in the tables at the foot of this page.
Getting the win/draw/loss right (choosing a win, draw or defeat) is worth 10 points. A perfect prediction earns forty points.
Ray, who competes for Gen City and Manchester City as well as England, is entering the fray at the eEuros finals after successfully navigating the qualification rounds.
The final eight competitors will represent their nations at the finals in a single-elimination, playing for a substantial cash prize and a coveted spot in the global championship qualifiers, with Denmark's Anders Vejrgang looking to retain the title he won last year.
"My mindset is really good for it," Ray said. "There's a really good coach with me and training has been going well.
"Representing your country is always an honour to play for your country. Naturally when you are younger, you fantasise about doing it as an professional footballer, but when you go into this profession and there is an opportunity to represent England, putting the shirt on is something unique.
"I beat Vejrgang 9-4 in qualifying to get here. I've played against him recently just in practice, and in other tournaments before - but I'd never beaten him in a tournament before.
"For me he is the number one in the world so getting a win over him in a tournament like this just provides a crazy boost of confidence."
Premier League Weekend Preview
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
The Blues were excellent against the Gunners at the end of November, when they secured a point after being reduced to 10 men, and I was thinking they've turned a corner, they could possibly be title contenders.
However, since that game, however, they were beaten physically by Leeds, looked uninspired against Bournemouth and this week got turned over by Atalanta in the Champions League.
So manager Enzo Maresca really needs a win here to restore momentum, but it won't be easy because the Merseyside club are such a threatening team.
Their key midfielders are playing really well and they have got a bit of a positive run at the moment.
Based on recent performances you would likely back Everton, while the most prudent prediction would probably be a draw, but I'm throwing caution to the wind.
They have not given me any good cause to back them recently, but I just have a gut instinct Chelsea will emerge victorious because they are at home and they are in need of three points.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I am at this game and it will be interesting to see what we get from Liverpool.
It was great to see for Reds boss Arne Slot to get such a great win at Inter Milan on Tuesday following all the stuff with Mohamed Salah this week.
Slot should not have to put up with that distraction. I know Salah has been a legend for Liverpool but at its core Slot just wants to win games and there is no ulterior motive in his team selection.
They changed their formation against Inter and went with a midfield diamond and two up top.
The media is going to be talking about whether Salah is back for this game, but the only way he is going to be brought back into the fold is if he apologises.
Slot's primary concern will be on winning this game, but it is a tough one.
It's fair to say it is the same for most teams but I find Brighton so unpredictable. I always feel they have got a goal in them, but they are defensively susceptible too.
The Merseysiders need to get back to winning consistently, but I am not sure how much their exertions at the San Siro will have taken out of them.
I put a couple of Brighton players in my FPL team, so they will probably lose now - but I do fancy them to get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
The Black Cats have had the opportunity to rest while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to let their lead slip away late on.
Aside from their excellent performance against Everton a couple of weeks ago, Newcastle's away form has been inconsistent, particularly straight after they've played in the Champions League.
I am expecting that tendency to continue on Sunday, and their fatigue is likely to be a significant issue in how this game goes because of their rivals' high press.
We saw how unwavering Regis le Bris's side are. They bullied the Gunners, and it was incredible to watch.
Commentators talks about how Granit Xhaka has been phenomenal for the Black Cats, and he has been brilliant, but Noah Sadiki, who plays alongside him, has also been one of the signings of the season and should be recognised too.
I am expecting this being the best game|most exciting fixture
